Smoked Turkey Grilled Cheese

Featured in: Core Meal Ideas

This savory and slightly sweet grilled sandwich combines smoked turkey breast, sharp cheddar cheese, and a tangy cranberry-Dijon spread, all melted together on golden toasted bread. Ready in just 18 minutes, it's an easy American-style sandwich perfect for lunch or a quick dinner. Layer your ingredients, butter the outside, and cook in a skillet until the cheese melts and the bread turns golden brown.

Updated on Sun, 18 Jan 2026 11:52:00 GMT
Golden toasted sourdough sandwiches filled with melted sharp cheddar, smoked turkey, and tangy cranberry spread. Save to Pinterest
Golden toasted sourdough sandwiches filled with melted sharp cheddar, smoked turkey, and tangy cranberry spread. | griddleaxis.com

My neighbor showed up one rainy November afternoon with leftover Thanksgiving turkey and a jar of homemade cranberry sauce. We stood in my kitchen trying to figure out what to do with it all, and I pulled out some cheddar and bread. What started as improvisation turned into the kind of sandwich I now crave year-round. The sweet-tart cranberry against smoky turkey and sharp cheese just works in a way that feels both comforting and a little fancy.

I made this for my brother once after he claimed grilled cheese was boring. He ate both halves in silence, then asked if I had more bread. Now every time he visits, he requests it by name, and I always keep cranberry sauce stocked just in case. It became our unofficial reunion meal, the thing that says welcome home without needing words.

Ingredients

  • Hearty sandwich bread: Sourdough holds up to the moisture from the cranberry spread and gives you those crispy, golden edges that make every bite satisfying.
  • Smoked turkey breast: The smokiness is key here, it deepens the flavor and makes the sandwich feel more layered than a simple deli meat stack.
  • Sharp cheddar cheese: You want something with bite to balance the sweetness, mild cheese just disappears in this combination.
  • Cranberry sauce: Whole berry or jellied both work, but whole berry gives little bursts of texture that I really love.
  • Dijon mustard: Just a teaspoon brings out the cranberry tang and keeps everything from feeling too sweet.
  • Unsalted butter: Softened butter spreads easily and gives you even browning without burning the bread before the cheese melts.

Instructions

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Make the cranberry spread:
Stir together cranberry sauce and Dijon mustard in a small bowl until smooth. This takes about ten seconds and makes all the difference.
Butter the bread:
Lay out your slices and spread softened butter on one side of each piece. The buttered sides will face outward when you assemble the sandwich.
Spread and layer:
Flip two slices over so the unbuttered side is up, then spread the cranberry mixture evenly across them. Layer the smoked turkey and cheddar on top, then cap with the remaining bread slices, buttered side out.
Heat the skillet:
Set a large skillet or griddle over medium heat and let it warm for a minute or two. You want steady, even heat, not a screaming hot surface.
Grill the sandwiches:
Place the sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently with a spatula. The bread should turn golden brown and the cheese should melt into gooey perfection.
Rest and serve:
Remove from the pan and let the sandwiches sit for a minute before slicing. This lets the cheese set just enough so it does not all slide out when you cut in.
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Smoked Turkey Grilled Cheese sandwich sliced diagonally, revealing layers of melted cheese and savory turkey. Save to Pinterest
Smoked Turkey Grilled Cheese sandwich sliced diagonally, revealing layers of melted cheese and savory turkey. | griddleaxis.com

One winter evening, I made these for a friend going through a rough patch. We sat at my little kitchen table with mugs of soup and these sandwiches, and she said it tasted like someone cared. That is when I realized food does not have to be complicated to matter, it just has to be made with attention and served with warmth.

Choosing Your Cheese

Sharp cheddar is my go-to, but Swiss brings a nutty sweetness that plays beautifully with cranberry. Gruyere makes it feel more grown-up and a little fancy, while smoked Gouda echoes the turkey and adds a deeper, almost campfire-like richness. I have tried them all, and honestly, none of them disappoint, so use what you love or what is already in your fridge.

Adding Greens

A handful of baby spinach or arugula tucked in with the turkey adds a peppery freshness that cuts the richness. I learned this after making the sandwich for a friend who always wants vegetables in everything. Now I keep a bag of arugula around just for this, and it turns the sandwich into something that feels a little more balanced and less like pure indulgence.

Serving Suggestions

This sandwich pairs beautifully with a simple green salad dressed in lemon vinaigrette or a pile of crispy sweet potato fries. I have also served it alongside tomato soup for the ultimate cozy lunch, and it works surprisingly well with a handful of kettle chips and pickles when you want something easy and satisfying.

  • Serve it with a handful of mixed greens tossed in olive oil and lemon for a light, bright contrast.
  • Sweet potato fries add a touch of sweetness that echoes the cranberry without overwhelming it.
  • If you are feeling nostalgic, a cup of tomato soup makes this feel like the best version of childhood comfort food.
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Close-up of a skillet-ready Smoked Turkey Grilled Cheese, featuring smoky turkey and cheddar on buttery bread. Save to Pinterest
Close-up of a skillet-ready Smoked Turkey Grilled Cheese, featuring smoky turkey and cheddar on buttery bread. | griddleaxis.com

This sandwich has become one of those recipes I make without thinking, the kind that feels like home no matter where I am. I hope it becomes that for you too.

Recipe FAQs

Can I prepare the cranberry spread ahead of time?

Yes, you can mix the cranberry sauce and Dijon mustard up to 24 hours in advance. Store it in an airtight container in the refrigerator and bring it to room temperature before assembling your sandwich.

What bread works best for this sandwich?

Hearty breads like sourdough or whole wheat are recommended for their structure and flavor. Avoid thin sandwich bread as it may tear when grilling. Brioche or ciabatta also work well for a slightly sweeter or more rustic profile.

How do I prevent the bread from burning while the cheese melts?

Cook over medium heat rather than high heat, and press gently on the sandwich as it cooks. This distributes heat evenly. If your heat source is particularly strong, reduce to medium-low and allow an extra minute per side.

What are some good cheese alternatives?

Swiss, Gruyère, and smoked Gouda are excellent substitutes for sharp cheddar. Each brings different flavors—Swiss adds mild nuttiness, Gruyère provides earthiness, and smoked Gouda intensifies the smoky profile of the turkey.

Can I add vegetables to this sandwich?

Absolutely. Baby spinach or arugula adds freshness and nutrition without overwhelming the flavors. You can also add thin tomato slices, roasted peppers, or caramelized onions for depth.

Is this sandwich suitable for meal prep?

The components can be prepped separately and stored in the refrigerator, but assemble and cook just before serving for the best texture. A pre-cooked sandwich won't have the same crispy exterior and melted cheese quality.

Smoked Turkey Grilled Cheese

A savory grilled sandwich featuring smoked turkey, sharp cheddar, and cranberry spread on golden toasted bread.

Prep Time
10 min
Time to Cook
8 min
Overall Time
18 min
Recipe by Gabriel Scott


Skill Level Easy

Cuisine American

Servings Produced 2 Serving Size

Dietary Notes None specified

What You'll Need

Sandwich

01 4 slices hearty sandwich bread, sourdough or whole wheat
02 4 oz smoked turkey breast, thinly sliced
03 4 oz sharp cheddar cheese, sliced or shredded

Cranberry Spread

01 3 tbsp cranberry sauce, whole berry or jellied
02 1 tsp Dijon mustard

For Grilling

01 2 tbsp unsalted butter, softened

Step-by-step Directions

Step 01

Prepare Cranberry Spread: In a small bowl, combine cranberry sauce and Dijon mustard, stirring until evenly blended.

Step 02

Butter and Arrange Bread: Lay out bread slices and spread a thin layer of butter on one side of each slice. Place buttered sides down on work surface.

Step 03

Apply Cranberry Mixture: Spread the cranberry mixture evenly on the unbuttered side of two bread slices.

Step 04

Layer Protein and Cheese: Arrange smoked turkey slices followed by cheddar cheese on top of the cranberry spread.

Step 05

Assemble Sandwiches: Top each assembled sandwich with remaining bread slices, ensuring buttered sides face outward.

Step 06

Heat Cooking Surface: Heat a large skillet or griddle over medium heat until uniformly warm.

Step 07

Toast Sandwiches: Place sandwiches in skillet and cook for 3 to 4 minutes per side, pressing gently with spatula, until bread achieves golden brown color and cheese melts completely.

Step 08

Rest and Serve: Remove sandwiches from pan, rest for 1 minute, then slice diagonally and serve immediately.

Necessary Tools

  • Large skillet or griddle
  • Spatula
  • Small mixing bowl
  • Bread knife

Allergy Details

Please check every ingredient for potential allergens and talk to a healthcare provider when unsure.
  • Contains gluten from bread products
  • Contains dairy including butter and cheese
  • Contains mustard
  • Contains poultry

Nutrition Details (per serving)

Nutritional info here is for guidance. Always speak with a medical professional if needed.
  • Energy (cal): 420
  • Fats: 20 g
  • Carbohydrates: 36 g
  • Proteins: 24 g